2 citations
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May 2016 in “Journal of dermatology” This letter discusses tissue expansion for correcting alopecia in a child with hypohidrotic ectodermal dysplasia, but provides no new experimental results.
This study found that PRP injections may safely improve penile curvature and PDQ scores in men with stable-phase Peyronie's Disease, although the curvature reduction observed was not enough to determine long-term clinical significance.
July 2024 in “Journal of Investigative Dermatology” Mechanical tension worsens keloid scars by activating inflammation and fibrosis pathways.
February 2024 in “Frontiers in physiology” This study examines the role of hair follicle stem cells in epidermal regeneration during skin soft tissue expansion, proposing a potential method for their cellular and molecular regulation.
October 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that applying the right mechanical stretch to skin can activate hair stem cells and promote hair regeneration through a pathway involving WNT, BMP-2, and M2 macrophages.
January 2019 in “Institutional Repositories DataBase (IRDB)” This study achieved regeneration of hair follicle-like structures and erector muscle of hair in vitro by simulating cellular organization and applying mechanical stimuli.
January 2019 in “Institutional Repositories DataBase (IRDB)” This study developed in vitro methods to regenerate hair follicles and erector muscles by mimicking their native structures and mechanical conditions, reconstructing hair follicle-like structures and forming muscle-like tissues.
January 2012 in “Jaypee Brothers Medical Publishers (P) Ltd. eBooks” Various surgical methods for hair restoration, like scalp reconstruction and tissue expansion, have been developed, but follicular unit transplant remains the most common procedure for correcting pattern baldness.
July 2002 in “Dermatologic Surgery” This study found that understanding the surgical anatomy of the scalp significantly improves outcomes in scalp surgery by reducing complications like unsightly scars and distorted hair patterns.
6 citations
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January 2013 in “Urology” This case report describes an 8-year-old child with penile tourniquet syndrome due to a constricting thread, which led to partial distal penile amputation and required surgical intervention.
163 citations
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April 2019 in “Nature Communications” This study found that mechanical skin stretching can stimulate hair stem cell proliferation and hair regeneration by activating a complex pathway involving WNT, BMP-2, and M2 macrophages.
67 citations
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December 2009 in “International Journal of Dermatology” This study suggests that hormonal receptor activity in skin regions undergoing mechanical stretching may influence extracellular matrix metabolism and the formation of SD, with variations in receptor functionality throughout lesion development stages.
19 citations
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April 2021 in “Stem Cell Research & Therapy” This study found that transplantation of autologous stromal vascular fraction cells increased skin thickness and improved regeneration when combined with mechanical stretching, without severe adverse events.
2 citations
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June 2021 in “Korean Journal of Food Preservation” This study found that adding red ginseng powder to string cheese before stretching the curd produced the highest sensory scores and maintained cheese hardness, suggesting it is optimal for manufacturing red ginseng string cheese.
11 citations
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April 2022 in “Biophysical Journal” In this study, certain cysteine residues in Romney sheep wool fibers were labeled more often during stretching tests, particularly under wet conditions, suggesting variability in their disulfide bond contributions to fiber mechanics depending on hydration.
This study found that anti-keratin antibody from immunized cow milk increases the resistance of damaged hair to stretching and inhibits fracture from excessive brushing.
49 citations
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June 2004 in “Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences” This study developed a multiscale model to understand human hair fiber mechanics and found that the yield stress decreases linearly with temperature, supported by both simulations and experimental stretching of hair fibers.
2 citations
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November 2023 in “Biomolecules” This review article analyzes the role of the WNT signaling pathway in skin development, wound healing, and mechanical stretching, emphasizing its importance in understanding and potentially advancing treatments for skin-related diseases.
January 2022 in “Journal of Orthopedic Practice” This study introduces modified skin boards with channels to retain lubricant on the skin, maintaining their effectiveness in stretching and flattening during harvesting.
70 citations
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February 2016 in “EMBO reports” This study identified a subtype of itch-sensing neurons in mice, which express Ret and somatostatin, and found that their ablation reduces scratching induced by certain pruritogens.
5 citations
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March 1981 in “PubMed” This case report details a 2-year-old girl who developed hypertrichosis on areas of her skin affected by multiple insect bites and subsequent scratching, resulting in unusual hair growth.
July 2024 in “Research Square (Research Square)” In this study, ATP-sensitive potassium channel openers, diazoxide and minoxidil, reduced scratching in cholestatic mice, suggesting these channels may play a role in cholestatic itch, while the channel blocker glibenclamide increased scratching behavior.
September 2023 in “Journal of Parasite Science” In this case report, a 12-year-old female pug mix dog diagnosed with demodicosis and a Malassezia infection showed improvement in symptoms after a week of treatment with antiparasitic drugs, antibiotics, antifungal medications, antihistamines, and vitamins, evidenced by reduced scratching intensity.
June 2026 in “Nature Communications” This study found that in stretch-mediated tissue expansion, fibroblasts adopt an embryonic-like, low-collagen state that enhances epidermal stem cell renewal, supporting coordinated skin expansion crucial for reconstructive surgeries.
January 2024 in “Veterinary Science and Medicine Journal” This case study reported successful treatment of ankylostomyosis and scabiosis in a three-month-old cat using ivermectin and pyrantel pamoate, improving symptoms significantly after three weeks.
88 citations
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April 2012 in “Journal of Investigative Dermatology” This study suggests that TRPV3 may play a key role in dry skin-related itch, indicating potential for TRPV3 antagonists in treating pruritus resistant to histamine H1R antagonists.
10 citations
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July 2011 in “Springer eBooks” This review describes the use of carbon dioxide for aesthetic treatments like skin rejuvenation and scar reduction but does not present new clinical findings.
9 citations
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July 2014 in “Skin research and technology” This study found that Caucasian hair is destroyed more easily than Asian hair when stretched, as indicated by changes in secondary structure, disulfide bond breakage, and physical disintegration.
8 citations
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September 2008 in “Medical Hypotheses” This article proposes a novel hypothesis that androgenetic alopecia may be mainly caused by skull bone expansion affecting blood supply to hair follicles rather than differences in individual follicle programming, and calls for more genetic research into skull development.
3 citations
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July 1987 in “Dermatologic Clinics” This article discusses scalp reductions for male-pattern baldness and reports potential challenges, such as stretch-back and scar-related styling issues, without providing new clinical results.