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GlossaryHeat Shock Proteins

help cells survive stress by stabilizing and refolding damaged proteins

Heat Shock Proteins (HSPs) are a group of proteins that are produced by cells in response to stressful conditions, such as elevated temperatures, toxins, or other environmental stressors. They function as molecular chaperones, helping to stabilize and refold damaged proteins, thereby protecting cells from stress-induced damage. HSPs are crucial for maintaining cellular function and integrity, and their role is significant in various biological processes, including protein homeostasis and the stress response.

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No Differences in Stress Protein Induction and Proliferative Capability in Follicular Unit Grafts Obtained by Follicular Unit Excision (FUE) and Follicular Unit Transplantation (FUT)

research No Differences in Stress Protein Induction and Proliferative Capability in Follicular Unit Grafts Obtained by Follicular Unit Excision (FUE) and Follicular Unit Transplantation (FUT)

1 citations , March 2019 in “Hair transplant forum international”

Both hair transplant methods, FUE and FUT, show similar stress responses and growth abilities in hair cells.

research The Role of Heat Shock Proteins in the Pathogenesis of Polycystic Ovarian Syndrome: A Review of the Literature

3 citations , January 2023 in “International Journal of Molecular Sciences”

Heat Shock Proteins are important in the development of Polycystic Ovarian Syndrome and could be targets for new treatments.

research Simulative Evaluation of Taurine Against Alopecia Caused by Stress in Caenorhabditis elegans

2 citations , January 2013 in “Advances in Experimental Medicine and Biology”

Taurine might help prevent hair loss caused by stress.

research Topical olive oil with downregulation of stress factors protects mice skin from precarious 3600 MHz electromagnetic radiation.

March 2020 in “The Egyptian Journal of Histology”

Topical olive oil protects mice skin from harmful electromagnetic radiation.

Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin

research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin

18 citations , October 2021 in “Frontiers in Physiology”

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

research Prevention of chemotherapy-induced alopecia in rodent models

27 citations , March 2008 in “Cell stress & chaperones”

Localized heat or specific injections can prevent chemotherapy-induced hair loss without affecting cancer treatment.

research Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences

April 2024 in “International journal of molecular sciences”

Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.

research Keratins in health and cancer: more than mere epithelial cell markers

438 citations , October 2010 in “Oncogene”

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

research Androgenic disorders

July 1996 in “Trends in Endocrinology and Metabolism”

The book is a valuable reference on androgenic disorders for professionals but not suitable for laypeople or medical students.

research Keratin intermediate filaments in the colon: guardians of epithelial homeostasis

38 citations , December 2020 in “International journal of biochemistry & cell biology”

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

research Development, Characterization, and Use of a Fetal Skin Cell Bank for Tissue Engineering in Wound Healing

71 citations , September 2006 in “Cell Transplantation”

Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.

research Heme Oxygenase and the Skin in Health and Disease

9 citations , October 2018 in “Current Pharmaceutical Design”

HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.

research Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth

4 citations , August 2021 in “Frontiers in Cell and Developmental Biology”

Stress can cause hair loss by affecting nerve-related hair growth, and noradrenaline might help prevent this.

research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases

80 citations , May 2018 in “Trends in Molecular Medicine”

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

research <p>L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes</p>

2 citations , August 2020 in “Clinical, Cosmetic and Investigational Dermatology”

The hair-growth formula with L-cystine helps protect and grow hair cells.

research Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility

189 citations , July 2009 in “The Journal of clinical investigation/The journal of clinical investigation”

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

research cis-Element- and Transcriptome-Based Screening of Root Hair-Specific Genes and Their Functional Characterization in Arabidopsis

188 citations , May 2009 in “Plant physiology”

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

research Prevention and treatment of alopecia areata with quercetin in the C3H/HeJ mouse model

29 citations , March 2012 in “Cell stress & chaperones”

Quercetin effectively treated and prevented hair loss in mice.

research Ectrodactyly, Ectodermal Dysplasia, and Cleft Lip/Palate Syndrome with Concomitant Lymphopenia: A Novel TP63 Mutation

February 2016 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

A new TP63 mutation was found in a baby with EEC syndrome, showing the need for TREC testing to check for immune issues.

research 1348 Changes in the aging dermal hair follicle environment in female scalp

May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Aging causes changes in scalp cells that can negatively affect hair health.

research 1350 Human scalp skin as an abundant and accessible source for eccrine sweat gland isolation and organ culture

May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Researchers found a new way to isolate sweat glands from the scalp for study and culture.

research 1351 Investigation of the molecular identity of the junctional zone in human

May 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

GATA6 is important for maintaining and differentiating cells in a key area of human skin.

research Possible Therapeutic Effects of Ozone Mixture on Hypoxia in Tumor Development

25 citations , February 2017 in “Anticancer Research/Anticancer research”

Ozone therapy might improve cancer treatment and reduce its side effects.

research Melanocytes and Vitiligo (and Hair Graying)

1 citations , January 2014 in “Elsevier eBooks”

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

research The Role of Histone Demethylases in Disease

1 citations , January 2011 in “Springer eBooks”

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

research Premature graying of hair

47 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

Premature graying of hair may suggest health issues and currently lacks effective treatments.

research Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis

47 citations , October 2004 in “Journal of Dermatological Science”

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

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Research

research No Differences in Stress Protein Induction and Proliferative Capability in Follicular Unit Grafts Obtained by Follicular Unit Excision (FUE) and Follicular Unit Transplantation (FUT)

research The Role of Heat Shock Proteins in the Pathogenesis of Polycystic Ovarian Syndrome: A Review of the Literature

research Simulative Evaluation of Taurine Against Alopecia Caused by Stress in Caenorhabditis elegans

research Topical olive oil with downregulation of stress factors protects mice skin from precarious 3600 MHz electromagnetic radiation.

research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin

research Prevention of chemotherapy-induced alopecia in rodent models

research Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences

research Keratins in health and cancer: more than mere epithelial cell markers

research Androgenic disorders

research Keratin intermediate filaments in the colon: guardians of epithelial homeostasis

research Development, Characterization, and Use of a Fetal Skin Cell Bank for Tissue Engineering in Wound Healing

research Heme Oxygenase and the Skin in Health and Disease

research Recent Progress in the Understanding of the Effect of Sympathetic Nerves on Hair Follicle Growth

research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases

research <p>L-Cystine-Containing Hair-Growth Formulation Supports Protection, Viability, and Proliferation of Keratinocytes</p>

research Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility

research cis-Element- and Transcriptome-Based Screening of Root Hair-Specific Genes and Their Functional Characterization in Arabidopsis

research Prevention and treatment of alopecia areata with quercetin in the C3H/HeJ mouse model

research Ectrodactyly, Ectodermal Dysplasia, and Cleft Lip/Palate Syndrome with Concomitant Lymphopenia: A Novel TP63 Mutation

research 1348 Changes in the aging dermal hair follicle environment in female scalp

research 1350 Human scalp skin as an abundant and accessible source for eccrine sweat gland isolation and organ culture

research 1351 Investigation of the molecular identity of the junctional zone in human

research Possible Therapeutic Effects of Ozone Mixture on Hypoxia in Tumor Development

research Melanocytes and Vitiligo (and Hair Graying)

research The Role of Histone Demethylases in Disease

research Premature graying of hair

research Different gene expression profile observed in dermal papilla cells related to androgenic alopecia by DNA macroarray analysis

research Skin Biology: Understanding Biological Targets for Improving Appearance

research A pilot study of ICG laser therapy of acne vulgaris: Photodynamic and photothermolysis treatment

research Low-level laser treatment accelerated hair regrowth in a rat model of chemotherapy-induced alopecia (CIA)