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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

New therapies are being developed that target integrin pathways to treat various diseases.

The project created a standardized system for classifying skin lesions in lab rats and mice.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Autophagy helps keep skin healthy and may improve treatments for skin diseases.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Certain bacteria from the Citrullus colocynthis plant may be a new source of antibiotics to fight drug-resistant diseases.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

Scientists can use engineered microbes to make L-aspartate and related chemicals, but there's still room to improve their efficiency.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

A 15-year-old girl has a skin condition causing blisters on her feet, likely inherited from her family.

Lotion with fucoidan from brown seaweed improved skin and reduced allergy symptoms in mice with dermatitis.

Protein profiling of forehead skin can help distinguish between frontal fibrosing alopecia and androgenetic alopecia.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.

Skin aging reflects overall body aging and can indicate internal health conditions.

Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

Vitamin D supplements may reduce hair-pulling in people with Trichotillomania.

The congress concluded that misuse of antifungal drugs in South Asia has led to widespread treatment failure, and new approaches and regional cooperation are needed.

Metformin for PCOS can rarely cause side effects like joint pain and behavior changes.

Skin bacteria, specifically Streptococcus and Staphylococcus, help in hair regrowth after skin injury and speed up wound healing.