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The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

Certain extracts from Curcuma aeruginosa Roxb. and germacrone can boost the skin's absorption of minoxidil, a hair growth promoter, making it more effective.

Hair follicles affect how well small molecules can pass through the skin, and this varies depending on the molecule's features.

The simulation showed that hypobaric pressure improves drug delivery through the skin, but stretching alone doesn't fully explain the increase.

Diffusion in artificial sebum is mainly influenced by molecular size and is much faster than in skin lipids.

Artificial sebum L closely mimics human sebum for drug delivery research.

Researchers developed a method to measure drugs in hair follicles and found that both water-loving and fat-loving drugs can be detected after being applied to the skin.

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

Ion-paired risedronate significantly increases skin penetration without irritation compared to risedronate alone.

The study found a way to improve a skin-applied minoxidil formula using a specific design method.

The document concludes that there is no agreed-upon best method for measuring drug delivery within hair follicles and more research is needed to validate current techniques.

Tea, especially green tea, shows promise in cosmetics for skin and hair benefits but more research is needed for effective use.

Hair absorbs molecules differently based on their size, charge, and love for water, and less at higher pH; this can help make better hair products.

Applying heat with certain chemicals can greatly improve how well isotretinoin gets into the skin through hair follicles.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

Eucalyptol and oleic acid in nanoemulsions improve minoxidil delivery to hair follicles, potentially enhancing hair loss treatment.

Finasteride-loaded microemulsions can effectively enhance skin delivery for treating hair loss.

New skin disease treatments using TDDS are improving but face challenges like side effects and high costs.

Minoxidil can be effectively encapsulated in coated nanovesicles for potential drug delivery.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

Niosomes are a promising and effective way to deliver drugs through the skin.

Adding TPGS to minoxidil solutions can improve skin penetration and retention, especially in water and PEG 400-based solutions.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.

Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.