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Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.

DDS treatment for LABD can cause severe side effects like anemia and hair loss, requiring careful monitoring.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Researchers found a new gene, hacl-1, that is active in mouse hair follicles during hair growth and may be important for hair biology.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Proretinal nanoparticles are a safe and effective way to deliver retinal to the skin.

Skin grafts are a common, minimally invasive way to close wounds in dogs, but better methods are still being sought.

The document concludes that recent research has improved understanding of skin diseases and the balance between cell growth and differentiation in the epidermis.

Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.

More precise, personalized therapies are needed for autoimmune diseases.

TGase 3 helps build hair structure by forming strong bonds between proteins.

Metallothionein likely helps in cell growth and development in wool follicles of fetal sheep.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.

Coconut seed extract may effectively treat scabies in rabbits by killing mites and reducing inflammation.

The chapter explains common scalp conditions, including infections, infestations, and tumors.

ING5 is crucial for stem cell maintenance and preventing certain cancers.

Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.

Regenerative medicine is effective and safe for treating vitiligo.

Hair follicles are valuable for regenerative medicine and wound healing.

Different skin diseases show unique patterns of skin cell separation, cell death, and granular layer changes.