research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
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research 25 Years of Epidermal Stem Cell Research
Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
research GRHL3 Binding and Enhancers Rearrange as Epidermal Keratinocytes Transition Between Functional States
GRHL3 is important for controlling gene activity in skin cells during different stages of their development.
research Keratin Disorders: From Gene to Therapy
New treatments targeting specific genes show promise for treating keratin disorders.
research Contribution of Environmental Constituents in the Genomic Disruption of Cytokeratins
Environmental factors can cause mutations in skin proteins, leading to skin disorders.
research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Near the Distal End of the Arrector Pili Muscle
Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
research Polymeric Micelle Mediated Follicular Delivery of Spironolactone: Targeting the Mineralocorticoid Receptor to Prevent Glucocorticoid-Induced Activation and Delayed Cutaneous Wound Healing
Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
research Evo Devo of the Vertebrate Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Thyroid Hormone Action in Epidermal Development and Homeostasis and Its Implications in the Pathophysiology of the Skin
Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.
research T Cell and Bacterial Microbiota Interaction at Intestinal and Skin Epithelial Interfaces
T cells and bacteria in the gut and skin help maintain health and protect against disease.
research Stem Cell Quiescence Acts as a Tumor Suppressor in Squamous Tumors
Inactive hair follicle stem cells help prevent skin cancer.
research Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
research Thyroid Diseases and Skin Autoimmunity
Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.
research Mechanical Forces in Skin Disorders
Skin problems can be caused or worsened by physical forces and pressure on the skin.
research Thiolated and PEGylated Silica Nanoparticle Delivery to Hair Follicles
Using longer PEG chains helps nanoparticles penetrate hair follicles better, improving drug delivery for conditions like alopecia.
research Skin Physiology in Microgravity: A 3-Month Stay Aboard ISS Induces Dermal Atrophy and Affects Cutaneous Muscle and Hair Follicles Cycling in Mice
A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
research Bioengineering a 3D Integumentary Organ System from iPS Cells Using an In Vivo Transplantation Model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research Self-Assembled Complete Hair Follicle Organoids by Coculture of Neonatal Mouse Epidermal Cells and Dermal Cells in Matrigel
Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
research Severe Hypernatremia as Presentation of Netherton Syndrome
Netherton syndrome can cause severe dehydration, infections, and growth issues in infants.
research Transfollicular Drug Delivery: Current Perspectives
Transfollicular drug delivery is promising but needs more research to improve and understand it better.
research Cell-Based Model Systems for Validation of Efficacy Claims for Cosmetic Ingredients
Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
research Trichofolliculoma on Gluteal Area: A Unique Case Report
A rare benign skin nodule was found on the buttock, a unique location for this condition.
research Panfolliculoma: Report of the Youngest Case and Literature Review of Its Histopathologic Variants
A 14-year-old boy is the youngest person reported with a rare, benign tumor related to hair follicles, usually found in older people.
research The Mineralocorticoid Receptor as a Novel Player in Skin Biology: Beyond the Renal Horizon?
The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.
research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle
Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway
Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
research Bioengineering Skin Constructs
Future research should focus on making bioengineered skin that completely restores all skin functions.
research Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research Molecular and Pathological Studies on Sarcoptes Scabiei in Sheep in Ismailia Province, Egypt
10.5% of sheep in Ismailia, Egypt, had Sarcoptes scabiei, causing skin issues.