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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

The Rotterdam Study aims to understand various diseases in older adults.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Fungi-produced compounds can change plant root growth.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Bioprinting could improve wound healing but needs more development to match real skin.

Stem cell self-renewal is complex and needs more research for full understanding.

Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.

The document concludes that a better understanding of cell changes during wound healing could improve treatments for chronic wounds and other conditions.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Different types of stem cells and their environments are key to skin repair and maintenance.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Finasteride effectively treats baldness but may cause sexual side effects.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.