Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reports that short exposure to vibration causes epithelial cells to retract filopodia, concentrate actin at their edges, and increase expression of the protease calpain, suggesting a mechanism for vibration-induced pain relief.

Mesotherapy and platelet-rich plasma treatments may help with hair loss, but their safety and effectiveness are still uncertain.

In this study, researchers introduced a machine learning approach to discover new nanozymes through the DiZyme platform, enabling the accurate prediction of multiple catalytic activities, and providing a comprehensive database and assistant resources for users.

This study found that finasteride treatment of male rats led to changes in their male offspring's testicular gene expression, potentially affecting sperm function in response to odorant-like signals.

This review examines the origins and mechanisms of tumor initiation in common skin cancers, but does not present new experimental findings; it emphasizes the need for further research on cancer stem cells.

This study used multiphoton microscopy to successfully visualize rabbit skin microstructure, highlighting its noninvasive potential for future skin research related to diseases and wound healing.

This review discusses the pathogenesis and clinical features of androgenetic alopecia, highlighting potential links to fibrosing alopecia and suggesting the need for combined therapeutic approaches; it reports no new clinical results.

This article describes a clinical case of a 67-year-old patient with telogen effluvium treated with a supplement containing amino acids, vitamin E, iron, and Serenoa repens, but reports no new clinical findings.

This review outlines recent advancements in understanding how micro-RNAs (miRNAs) influence hair regeneration, highlighting their role in stimulating hair growth and potential therapeutic approaches, while also addressing the challenges of clinical translation due to miRNAs' complex roles and delivery issues.

This study identified a group of dermal fibroblasts near hair follicle stem cells in mice that facilitate hair regeneration by creating a biomechanically compliant extracellular matrix, enhancing stem cell activation and promoting a positive feedback loop for tissue regeneration.

This review examines advancements in "smart" hydrogel dressings for complex wound healing, highlighting innovations in materials that provide multifunctionality, such as responsive drug delivery and regenerative capabilities. The study also addresses potential challenges in clinical application, like manufacturing and regulatory hurdles.

This review discusses recent advancements in nanotechnology for treating hypertrophic scarring and atopic dermatitis, highlighting the potential of nanotherapeutic platforms in enhancing therapeutic effects by modulating the skin's microenvironment.

This study developed a novel regenerative platform using nanozyme-enabled materials combined with exosomes and laser stimulation to enhance wound healing in a mouse model, which more effectively regulated reactive oxygen species and improved early angiogenesis and collagen organization compared to conventional methods.

This study found that mice exposed to low humidity showed altered epidermal gene expression, which was modulated by topical emollient application; this suggests emollients may help manage dry skin in low-humidity environments by affecting specific gene pathways.

This study in male rats identified a unique type of mechanoreceptor, the club-like ending, which responds only to touch and not to self-motion during whisking, contrasting with other receptors that show mixed selectivity.

This study found that miRNA-24 downregulates the KLF6 gene, influencing coat color by affecting melanogenesis pathways in Cashmere goats, and that miRNA-24 inhibition increased melanin content in mice.

This study found that umbilical cord mesenchymal stem cell-derived exosomes improved hair growth in mice with androgenetic alopecia by promoting hair follicle stem cell stemness through the RAS/ERK pathway, suggesting a potential new treatment strategy for this condition.

This study found that patients with SARS-CoV-2 associated telogen effluvium experienced hair loss sooner after infection compared to telogen effluvium from other causes, with distinct dermoscopic findings aiding diagnosis.

This review discusses the potential for surface-modified nanostructured lipid carriers to enhance hair regrowth by improving drug absorption and stability, focusing on their use with agents like minoxidil and finasteride for hair loss treatment.

This review discusses the potential and current applications of platelet-rich plasma in otolaryngology and reports no new clinical results; the authors note varying evidence for its effectiveness across medical conditions.

In this study, researchers analyzed skin samples from Dorper sheep to identify 395 differentially expressed long non-coding RNAs (lncRNAs) linked to hair follicle growth phases, suggesting these lncRNAs may play a role in the regulation of hair shedding through pathways like estrogen and PI3K-Akt signaling.

In this study, the authors propose that drugs like trazodone and antipsychotics such as chlorpromazine, which can induce priapism, may help restore libido synaptic circuits, offering potential treatment for post-finasteride syndrome and post-SSRI sexual dysfunction.

In this study, Trichophyton tonsurans and Microsporum canis were identified as the primary causes of tinea capitis, with terbinafine treatment showing the highest cure rate. Non-commercial kits surpassed real-time PCR commercial kits in specificity and sensitivity for diagnosis.

This study found that miR-23b and miR-133 significantly reduce mRNA and protein levels of specific target genes involved in Merino sheep hair follicle development, providing insight into molecular breeding for fine wool production.

This study found that dermal injection of M-CSF stimulated CD11b + myeloid cells can induce alopecia areata in mice by potentially activating B lymphocytes, offering insight into the disease's pathogenesis.

This study found that repeated use of a protein hair conditioner, followed by hot air and gamma irradiation, may lower serum collagen I and increase heat shock protein concentrations in rats, suggesting potential cumulative risks.

This study introduces a modular fiber model to investigate how changes in microstructural properties of wool affect its critical buckling load, highlighting potential uses and areas needing further research in wool fiber biophysics.

This study found that hair follicle stem cells in mice have an unexpected ability to adaptively determine their differentiation pathways, maintaining tissue architecture despite external stimuli.

In this study, researchers found that stabilizing the protein HIF1A in hair follicles promotes glycolysis over oxidative phosphorylation, potentially reducing oxidative stress and supporting hair growth.

This study suggests that human hair follicles may operate their own Cori cycle, synthesizing glycogen from lactate under conditions of lactic acidosis.