Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that the phytosterols β-sitosterol, stigmasterol, and campesterol have low-to-negligible inhibitory activity against steroidal 5α-reductase type 2 compared to the synthetic inhibitor dutasteride, with β-sitosterol showing the highest activity among the tested phytosterols.

This study reports that using molecular docking methods, beta-sitosterol and stigmasterol from Serenoa repens were identified as potential natural inhibitors of the 5AR1 enzyme, which could serve as novel treatments for androgenetic alopecia based on their inhibitory action observed in a laboratory setting.

This study reported that a large proportion of US adults with physician-diagnosed alopecia areata experience substantial emotional and mental health comorbidities and report significant stigma across all disease severities, yet few are receiving counseling or therapeutic intervention.

This cross-sectional survey found that individuals with alopecia areata and androgenetic alopecia perceived stigmatization and impaired quality of life, with greater stigma reported in German-speaking participants; factors like gender, age, and disease severity influenced stigmatization levels.

This study explored the potential of stigmasterol as a treatment for androgenetic alopecia through various simulation techniques, finding promising interactions with key genes involved in hair loss, but further experimental validation is needed before clinical application.

This cross-sectional survey study found that stigmatizing attitudes toward people with alopecia are present in various social and professional settings, with stigma levels varying by alopecia severity and perceptions of its medical nature.

This observational study provides cause-specific mortality estimates to help patients and physicians better understand long-term outcomes for localized prostate cancer based on initial treatment choices.

This review found that despite varied levels of stigmatization reported in studies, hair loss generally leads to stigmatization and a reduced quality of life, but specific research on this stigma is limited.

This study found that the psychosocial impact of AA is more strongly related to patients' illness perceptions and stigma than to the severity of the disease.

This study examined perceptions of stress as a cause of alopecia areata among individuals in a French online cohort, finding that over half of patients considered stress a contributing factor. Additionally, patients with less understanding of their condition experienced higher levels of perceived stigma.

This study found that 54% of alopecia areata patients attributed their condition to stress, which was linked to higher perceived personal control and significant emotional impacts.

This study found that vitiligo elicited the most compassion and curiosity among general adults viewing AI-generated images of chronic skin diseases, while psoriasis was linked to higher perceptions of disgust and blame.

This clinical image report discusses a 50-year-old male with ethanol-related chronic liver disease who, despite showing signs of Dupuytren Disease, was asymptomatic and therefore did not receive treatment.

This observational study found that patients with various skin diseases across 17 European countries experience higher levels of perceived stigmatization than skin-healthy controls, particularly those with psoriasis, atopic dermatitis, alopecia, and bullous disorders, with factors such as disease severity and psychological distress influencing stigmatization levels.

This review identified several changeable psychosocial factors, like acceptance, as potential targets for interventions aimed at reducing self-stigma and improving mental health in affected individuals.

This study demonstrated that individuals with alopecia areata in Japan experience significant stigma and mental health issues, with perceived stigma and dissatisfaction with hair growth negatively correlated with disease severity.

This study found that self-stigma is common among alopecia areata patients, with 85% experiencing it to some degree, and that factors like increased social support and illness acceptance correlate with lower stigmatization levels, while helplessness correlates with higher levels.

In this study, a mixed-methods survey of 357 balding men revealed that baldness is structurally stigmatized, with many participants experiencing distress and using treatments to combat it; others resisted stigma and expressed minimal distress.

In this narrative review, the authors found that stigma related to oculocutaneous albinism in Africa is primarily driven by socio-cultural beliefs and structural inequities, affecting individuals' health, education, and psychosocial well-being, with interventions needed to dispel myths and provide specialized healthcare and support.

This study found that participants perceived bald men more negatively based on facial expressions and reported varied body dissatisfaction, which was weakly linked to wellbeing and muscularity behaviors.

In this review, the authors reported that past concerns linking spironolactone to an increased risk of breast cancer are unfounded, citing recent studies that confirm no such association, indicating spironolactone's potential as a treatment for alopecia in women without fear of cancer recurrence.

This study found that follicular unit transplantation effectively corrected postrhytidoplasty stigmas like visible scars or displaced hairlines, with high patient satisfaction and a low complication rate.

This article discusses techniques to avoid common signs of facial rejuvenation surgery and reports no new clinical results; it emphasizes preventing recognizable outcomes like unnatural hairlines and ear deformities.

A girl with red hair developed hair-pulling and body image disorders after being bullied for her hair color.

In this study, researchers identified that three homologous genes—ZmSPL10, ZmSPL14, and ZmSPL26—are crucial for the development of stigmatic papilla in maize, with triple knockout mutants lacking these genes showing almost no stigmatic papilla and significantly reduced kernel setting.

This case report highlights the use of microarray analysis to identify cryptic chromosomal rearrangements in a young woman with intellectual disability and multiple congenital anomalies.

In this population-based study, researchers reported that nearly half of Greek adults experienced at least one skin condition in the past year, with significant impacts on quality of life, work decisions, and perceptions of stigmatization.

In this study, cancer patients aged 30 to 50 reported experiencing diagnostic delays, coping through self-advocacy, and facing stigma-related challenges such as alopecia. The authors concluded that improved physician awareness, tailored screening, and addressing stigma are essential for enhancing care for early-onset colorectal cancer patients.

This study found that Phyllanthus urinaria extract displayed significant anti-alopecia properties in a mouse model, showing potential as an anti-5α-reductase agent for androgenic hair loss.

This study found that ethanolic and petroleum ether extracts of Cuscuta reflexa, as well as an isolate from these extracts, improved hair growth and follicle characteristics in androgen-induced alopecia in rats.