110 citations
,
February 2024 in “Journal of Chemical Information and Modeling” This study describes the PandaOmics platform, which uses AI and bioinformatics to identify new therapeutic targets and biomarkers for various diseases, demonstrating validation in laboratory and animal studies.
82 citations
,
July 2022 in “Bioengineering & Translational Medicine” This review examines how biochemical and biophysical induction factors influence cell fate in tissue engineering and reports no new experimental results.
32 citations
,
December 2015 in “PloS one” This study found that applying a topical inhibitor of TGF-β1 may enhance scar maturation and improve the appearance of hypertrophic scars in a nude mouse model after two weeks.
28 citations
,
November 2020 in “Polymers” This study found that crosslinking buffalo gelatin with different methods can modify its properties and potential as a skin substitute, though double-crosslinking may increase immunogenicity slightly.
13 citations
,
October 2016 in “Acta Biochimica et Biophysica Sinica” This study found that GhPLDα1 in upland cotton may be involved in fiber development, correlating with increased hydrogen peroxide and cellulose biosynthesis during secondary cell wall thickening.
12 citations
,
June 2023 in “International Journal of Molecular Sciences” This review examines the potential of biomaterial-based wound dressings in managing diabetic foot ulcers, highlighting their versatility and therapeutic properties for promoting wound healing in individuals with diabetes mellitus.
11 citations
,
July 2024 in “Biomimetics” This manuscript explores the development and future potential of injectable biomimetic gels in biomedical applications, highlighting their promise in wound healing and tissue regeneration, while also acknowledging challenges like mechanical durability and scalable production still persist.
7 citations
,
August 2023 in “Skin Research and Technology” This study highlights age and sex as key factors influencing scalp parameters, thereby affecting hair health and suggesting they should be considered in developing hair care strategies.
6 citations
,
June 2024 in “Gels” In this study, researchers used 3D printing combined with cryogenic crosslinking to develop gelatin/oxidized alginate scaffolds and found that adding 5% hydroxyapatite improved mechanical properties and osteogenic effects, enhancing bone tissue regeneration, though 10% hydroxyapatite offered no additional osteogenic benefits and reduced shape fidelity.
3 citations
,
June 2023 in “MedComm” This study summarizes the role and potential applications of stem cell exosomes in skin and bone healing, highlighting their regenerative capabilities and suggesting innovative delivery methods like nanoliposomes and hydrogels to improve bioavailability and therapeutic outcomes.
2 citations
,
October 2025 in “Chinese Medicine” This review article summarized the design, synthesis, and application of innovative delivery systems for berberine, highlighting their potential to enhance wound healing through improved bioactivity and bioavailability, particularly in challenging conditions like diabetic and infected wounds.
2 citations
,
May 2023 in “Cancer medicine” This review reports that KRT80 is overexpressed in various cancers, enhancing cancer cell proliferation, invasiveness, and migration, suggesting it as a potential therapeutic target, though more clinical studies are needed to fully understand its role in cancer prognosis.
2 citations
,
August 2019 in “Electronics and Communications in Japan” This study reports a highly sensitive MEMS silicon-hair device that mimics hair follicle functions by detecting minimal forces and moments, including electrostatic attraction and surface tension of liquids.
1 citations
,
January 2010 in “Biological and medical physics series” This review discusses past research on the chemical and physical properties of human hair, focusing on structural analysis and mechanical property measurements with methods like SEM and tension tests, but adds no new findings.
August 2026 in “Pharmaceuticals” This review reports that biopolymer-based hydrogels show promise as wound dressings due to their biocompatibility, moisture retention, and ability to mimic the extracellular matrix, though challenges in mass production, safety, and clinical validation remain.
May 2026 in “Journal of Dermatological Science” This review highlights that collagen XVIIα1's role in maintaining dermal-epidermal junction integrity and hair follicle stem cell maintenance is compromised with age due to reduced levels and increased processing, potentially affecting skin and hair aging.
February 2026 in “Preprints.org” This review synthesizes the latest advances in wound healing and scar management, exploring molecular mechanisms, therapeutic strategies, and providing an evidence-based comparison of topical agents like Dermatix Ultra and Contractubex for scar improvement, aimed at informing clinicians and patients in decision-making.
February 2026 in “Exploration” This review summarizes research on scar formation and inhibition mechanisms, discussing emerging therapies like gene therapy and stem cell treatments, but notes ongoing challenges for clinical application, including treatment personalization and outcome sustainability.
October 2025 in “International Journal of Cosmetic Science” This study observed that hair properties vary by ethnicity, influenced by genetic, environmental, and cultural factors, and noted that ethnicity-dependent differences in surface charge and other properties warrant further investigation.
October 2024 in “Applied Sciences” In this study, tubular 3D bioprinted structures made from sodium alginate and gelatin, containing NIH/3T3 fibroblast cells, demonstrated the ability for cell growth and network formation over 6 weeks, although structural tensile strength decreased with cell growth and polymer degradation.
606 citations
,
January 2016 in “International Journal of Cell Biology” This review outlines recent advances in stem cell and tissue engineering technologies in regenerative medicine and wildlife conservation, reporting no new clinical results.
488 citations
,
July 2021 in “Cell” This review discusses the development, lineages, functions, and roles of fibroblasts in fibrosis across four organs, highlighting their capabilities in tissue repair and contributions to fibrotic disorders when aberrantly activated, but it reports no new experimental findings.
227 citations
,
April 2020 in “Cell” This review highlights the ongoing challenges and advancements in developing precise and early intervention strategies for autoimmune diseases and emphasizes the need for more personalized and disease-specific therapies.
203 citations
,
July 2017 in “Biotechnology and Genetic Engineering Reviews” This review discusses the various components essential for successful tissue engineering, such as cell sources, modification methods, and supportive matrices, and highlights the need for functional synergy without reporting new experimental results.
113 citations
,
June 2019 in “F1000Research” This review discusses the mechanisms of wound healing and excessive scarring, highlighting the importance of understanding these processes for developing new therapies to prevent fibrotic scarring in large skin wounds.
98 citations
,
December 2015 in “The Journal of Cell Biology” In this study, researchers found that the absence of type I or type II keratins in mice leads to severe skin barrier defects, highlighting keratins' crucial role in epidermal structure and function.
96 citations
,
October 2021 in “Reproductive Sciences” Women with PCOS often experience depression and anxiety, affecting their quality of life.
89 citations
,
January 2021 in “Molecules” This review discusses the applications of biopolymeric composites in controlled drug release, tissue engineering, and wound healing, but reports no new experimental results, highlighting the need for further development and analysis.
81 citations
,
March 2022 in “Frontiers in Bioengineering and Biotechnology” This review discusses advancements and challenges in bioengineered scaffolds for wound healing but presents no new experimental findings, highlighting their potential and need for further development.
78 citations
,
February 2024 in “ACS Omega” This study developed a bilayer material combining poly(vinyl alcohol) and bacterial cellulose with a gelatin-poly(vinyl alcohol) hydrogel, showing strong potential as a wound dressing due to its good antibacterial properties, cell viability, and sustained drug release.