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This review discusses the biological roles and diagnostic significance of keratins in mammalian colon epithelial cells and reports no new clinical results.

This review discusses the role of polarity signaling in coordinating tissue mechanics, micro-environmental functions, and cell fate decisions, but it reports no new results, highlighting the need for further study in mammalian models.

This review summarizes the roles of matricellular proteins in skin stem cell niches, highlighting their contribution to stem cell fate, self-renewal, and potential implications for wound healing and aging.

This study developed a 3D bioprinted skin model to mimic pemphigus vulgaris, providing a tool to study disease mechanisms and test targeted therapies by reproducing the architecture and pathogenic disruptions of native skin.

This study found that a nano-preparation of quercetin, using a self-nanoemulsifying drug delivery system, was more effective than standard quercetin in reducing cardiac complications and tissue damage in rats with metabolic syndrome, although both formulations similarly reduced oxidative and inflammatory markers.

This study reported that newly developed RADA16-I peptide hybrids, with active motifs like GHK and KGHK, demonstrated improved wound healing in a mouse skin injury model without cytotoxicity, suggesting they might be effective scaffolds for tissue engineering and regeneration.

This study reports a method for fabricating biofunctional polymer fibers by using DNA-programmable cell-free protein synthesis integrated through solution blow spinning, enabling in situ protein production and potential applications in respirators, sampling swabs, and other advanced materials.

This review discusses the genetic and biological factors influencing hair curliness, revealing strong links to specific protein variations, and reports no new clinical results.

In this study, researchers found that human fingerprint ridges are formed through a modified hair follicle developmental process and spatial patterns influenced by specific signaling pathways.

This review highlights the role of keratin mutations in epidermolysis bullosa simplex and the resulting chronic inflammation, but it presents no new experimental findings.

This study found that intermittent treatment with FTI lonafarnib and sulforaphane may be a promising therapeutic approach for children with Hutchinson-Gilford progeria syndrome, as it improved the cellular phenotype.

This review discusses the role of tissue mechanics and extracellular matrix in skin aging processes and highlights potential therapeutic strategies, but reports no new clinical results.

In this review, the researchers highlight the role of fibroblasts in regulating the extracellular matrix and immune responses, emphasizing the impact on macrophages and potential therapeutic insights for fibrotic diseases and cancer.

In this study, researchers developed gellan gum hydrogels functionalized with biomimetic peptides that create a supportive microenvironment for human dermal papilla cells, enhancing their hair-inductive capacity and ability to mimic hair morphogenesis-like events in vitro.

This review discusses the potential benefits of hyperthermia in cancer therapy, combined with natural compounds, to enhance treatment efficacy and reports no new clinical results.

This review discusses advancements in skin microphysiological systems, such as 3D bioprinting, skin organoids, and skin-on-a-chip, and their effectiveness in emulating human skin functions for research and preclinical applications, highlighting the potential for replacing animal testing with these innovative technologies.

In this study, researchers developed an axolotl skin-derived extracellular matrix scaffold that enhanced wound healing in mice by promoting skin regeneration and reducing fibrosis, offering potential as a regenerative biomaterial for clinical use.

In this study, researchers reported that hair follicle stem cells maintain quiescence through a PIEZO1-dependent mechanism that senses mechanical forces and translates them into localized calcium influx, involving a transcriptional network that regulates cell adhesion and cytoskeleton-related genes.

This study found that in female mice, softer, lightly crosslinked gelatin-based hydrogels promoted better wound healing with less scarring and inflammation compared to stiffer, heavily crosslinked hydrogels, affecting immune and stromal cell behavior.

This review explores the application and implications of 3D bioprinting in plastic surgery but reports no new clinical results, emphasizing its potential benefits and challenges for future research.

This study introduces a novel in vitro model for clubfoot fibrosis to enable high-throughput drug screening and found that while the model increased collagen deposition, the antifibrotic drug minoxidil effectively inhibited the expression of collagen cross-linking enzymes.

In this study, the researchers developed a hydrogel mimicking the fetal environment that significantly accelerated wound healing and hair follicle regeneration in vivo, with over 94% wound closure in 14 days, surpassing hydrogels lacking certain additives.

This review discusses the commonly observed pathological findings in progeroid mouse models and highlights the importance of understanding mouse strain backgrounds and progeria-related phenotypes for accurate pathology data interpretation.

This review article highlights recent advancements in smart hydrogels as promising solutions for diabetic wound management, emphasizing their ability to respond to wound environments and deliver targeted therapies, while addressing limitations of traditional dressings.

This study identified morphotype-specific gene expression patterns in feathers, enhancing understanding of the molecular and cellular processes involved in feather development and diversification.

This review discusses the role of fascial mobilization in wound healing and its potential implications for treating chronic skin wounds and scarring, but reports no new clinical results.

Understanding tissue self-organization can improve treatments for diseases and advance regenerative medicine.

This review highlights how organoid technology is transforming precision medicine by summarizing its development and applications in modeling diseases, testing drug efficacy, and tailoring patient-specific treatments, despite current challenges in standardization and ethical considerations.

This study observed that lipids in human hair accumulate in specific areas and do not significantly impact water permeability, highlighting the utility of AFMIR for studying complex biomaterials.

This review explores the role of transient receptor potential vanilloid channels in the pathogenesis of osteoarthritis but reports no new clinical results.