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Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Vegetable protein lowers cholesterol and protein deficiency can cause health issues.

Polycystic ovary syndrome (PCOS) was first described in 1721, officially diagnosed in the 1990s, and is now known to be partly genetic and linked to insulin resistance, with increased risk of cardiovascular disease and carbohydrate metabolism issues.

Many infertile women with PCOS in Central Vietnam have metabolic or insulin resistance syndrome, with obesity and older age increasing the risk.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.

An mFG score of 7 or higher indicates hirsutism in Filipino women, often linked to higher free testosterone levels.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Hormones are crucial for regulating body functions and imbalances can lead to health issues.

Finasteride may lower cholesterol and slow heart disease progression.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

Vertical sleeve gastrectomy improved metabolism, behavior, and reproduction in obese rats with PCOS.

AMH helps estimate ovarian reserve but doesn't predict pregnancy chances; age is more important.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Medications for PCOS don't seem to raise heart disease risk.

Polycystic Ovary Syndrome (PCOS) in teenagers is a complex condition linked to genetics and environment, often associated with obesity and insulin resistance, and is treated with lifestyle changes and medication.

Melatonin improved mental health and metabolism in women with PCOS.

Testosterone therapy may slightly increase sexual desire in women with HSDD but lacks broad recommendation due to safety concerns and limited approval.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Indian women with PCOS may need different ultrasound criteria for diagnosis than current standards.

Family members of North Indian women with PCOS have a high rate of metabolic syndrome.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.