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Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

AMH levels can't reliably tell the difference between LOCAH and all types of PCOS in women with excessive hair growth.

Married women with type 2 diabetes had a surprisingly low infertility rate, suggesting type 2 diabetes and PCOS may be different conditions.

Many young Egyptian women with PCOS also have fatty liver disease, especially if they are overweight and insulin resistant.

Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Indian jujube has many medicinal properties and can help treat ailments like diabetes, inflammation, and cancer.

A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.

An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Gene mutations can cause problems in male genital development.

The article concludes that hormonal therapy is an effective long-term acne treatment, even for those without hormonal imbalances.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.