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Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Lipin-1 is important for skin cell differentiation and skin barrier function.

Finasteride may increase depression by reducing brain cell growth.

Finasteride may improve prostate cancer treatment outcomes.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Centratherum anthelminticum seed extract effectively treats Polycystic Ovary Syndrome in rats.

The document explains how male reproductive hormones work and affect the body.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Indian jujube has many medicinal properties and can help treat ailments like diabetes, inflammation, and cancer.

Cuscuta reflexa extracts and an isolate promoted hair growth and could be natural treatments for hair loss.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

The document concludes that effectively managing PCOS requires a multifaceted approach.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

PCOS in lean women is a serious health condition with implications beyond fertility, affecting metabolism and increasing cardiovascular disease risk.

Chromium salts may help with insulin sensitivity in PCOS, but more research is needed to confirm their overall effectiveness and safety.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.