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Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Asian hair is generally straight and thick, with unique disorders and properties, and more research is needed to understand it fully.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Insulin-lowering medications show promise for PCOS symptoms but can't be the main treatment yet due to limited long-term research.

Adrenal disorders can cause lasting brain and behavior issues in children.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

A male with aromatase deficiency improved bone health with estradiol treatment.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Large prostate links to more hair loss, but age of onset doesn't affect it.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.