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Sebocytes play a key role in controlling androgen levels in human skin.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Finasteride effectively treats baldness but may cause sexual side effects.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.