research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
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research Treatment of Hyperandrogenism in Polycystic Ovary Syndrome
Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.
research Primary Scarring Alopecias
The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
research Polycystic Ovary Syndrome: Overview and Management
PCOS is a common hormonal disorder in women, treated with lifestyle changes, medication, and patient education.
research Effective Medical Treatment for Common Baldness in Women
Antiandrogen therapy helped increase hair growth in women with hormonal imbalances related to baldness.
research Disorders Linked to Insufficient Androgen Action in Male Children
Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.
research Nanotechnology in Dermatology
Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
research Shedding Light on Therapeutics in Alopecia and Their Relevance to COVID-19
Some alopecia treatments might help treat COVID-19, but more research is needed.
research Letter to the Editor on COVID-19 Infection in Men on Testosterone Replacement Therapy
The letter suggests testosterone replacement therapy might worsen COVID-19 outcomes.
research Hair Sciences: An Interview with Dr. Rodney Sinclair on Female Pattern Hair Loss
Dr. Rodney Sinclair uses a detailed grading system to diagnose female pattern hair loss, recommends daily spironolactone and minoxidil for treatment, and believes genetics play a role in the condition.
research New Developments in Our Understanding of Acne Pathogenesis and Treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research Molecular Epidemiology of Hypospadias: Review of Genetic and Environmental Risk Factors
Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
research Hormonal and Surgical Treatment Options for Transgender Women and Transfeminine Spectrum Persons
Transgender women can develop feminine traits and improve their quality of life through hormone therapy and surgery, but results vary and access to surgery can be limited.
research Managing Dermatologic Effects of Gender-Affirming Therapy in Transgender Adolescents
Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.
research Effect of Gender-Affirming Hormone Therapy on Hair Growth: A Systematic Review of the Literature
Gender-affirming hormone therapy changes hair growth in transgender people, with feminizing therapy reducing hair and masculinizing therapy increasing it, but sometimes additional treatment is needed.
research Female Pattern Hair Loss: Therapeutic Update
Topical minoxidil is the best-supported treatment for female hair loss, but personalized plans are needed.
research Hirsutism: A Comprehensive Update of Embryology, Aetiopathogenesis, and Therapeutic Approach
The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.
research Use of Spironolactone in Dermatology
Spironolactone is used in dermatology to treat skin conditions related to hormones, but is not safe for pregnant women or men.
research Substantiation of Technological Parameters of the Oil Extract Obtained from Urtica Dioica Roots Based on the Yield Determination of Phytosterols Using Capillary Gas Chromatography Method
The best way to extract oil from Urtica dioica roots is by using corn oil, a 1:5 ratio of raw material to extract, extracting for 6 hours, and using the maceration method.
research Is There a Role for Antiandrogen Therapy for Hidradenitis Suppurativa? A Systematic Review of Published Data
Antiandrogen therapy for hidradenitis suppurativa lacks strong evidence and needs more research.
research Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.
research Improvement of Alopecia and Decreases in Hair Cortisol and Dihydrotestosterone Concentrations After the Topical Use of Plant Extracts in Men With Androgenetic Alopecia
Plant extracts in shampoo improved hair thickness and density in men with hair loss.
research The Immune Response to COVID-19: Does Sex Matter?
Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.
research Impact of Medical Castration on Malignant Arrhythmias in Patients With Prostate Cancer
Medical castration in prostate cancer patients can increase the risk of serious heart rhythm problems, so it's important to monitor heart activity during treatment.
research Polycystic Ovary Syndrome: A Comprehensive Review of Pathogenesis, Management, and Drug Repurposing
PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.
research Androgenetic Alopecia
Androgenetic alopecia is a common hair loss condition caused by testosterone effects on hair follicles, leading to thinner, shorter, and less pigmented hair, diagnosed using scalp dermoscopy and treated with topical minoxidil, antiandrogen agents, and 5-alpha reductase inhibitors.
research Autistic-Undisciplined Thinking in the Practice of Medical Trichology
The article concludes that treating hair loss requires careful research, understanding the causes, and personalized treatment plans.
research Gene Expression of Type 2 17β Hydroxysteroid Dehydrogenase in Scalp Hairs of Hirsute Women
Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
research Polycystic Ovary Syndrome (PCOS): An Inflammatory, Systemic, Lifestyle Endocrinopathy
PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.