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A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.

Cyclophosphamide helped 59.4% of children with steroid-resistant nephrotic syndrome but caused side effects in 40.6%.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.

Cyclosporine may cause hair loss, so patients need monitoring.

Rituximab may be an effective treatment for Cronkhite-Canada syndrome with kidney disease.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Myasthenia gravis can affect both motor and non-motor systems due to immune system issues.

PCOS is linked to diabetes and insulin resistance, and managing AGEs may help treat related symptoms.

Skin problems from transplant drugs are common and need careful management in organ transplant patients.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Targeted therapies for lung cancer are effective but require careful management of side effects to benefit patients.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

Skin doctors should know about skin and kidney disease links to prevent serious kidney problems.

Antihelminthic drugs treat worm infections but face challenges like low treatment coverage and potential drug resistance, with various side effects reported for different drugs.

Atopic dermatitis may have genetic causes and can be treated with pharmacologic methods, glycerin creams, and controlling Staphylococcus aureus colonization.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Treatments for melanin disorders exist, but more effective options needed.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Fever and rash can be early signs of lupus.

Glucocorticoid treatment in lupus can cause oral lesions, which need early diagnosis and comprehensive care.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.