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Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

Graphene oxide and indole-3-acetic acid together inhibit root growth in Brassica napus L. by affecting multiple plant hormone pathways.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.

Effective PCOS treatments require targeting specific signaling pathways.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Some breast cancer chemotherapy can cause permanent hair loss.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Parathyroid hormone-related protein helps control hair growth phases in mice.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.

Found key genes affecting hair loss, immune response, and skin development; more research needed for better treatments.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

Certain microRNAs in the fluid around eggs are linked to Polycystic Ovary Syndrome and may help diagnose it.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.