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GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

Mycophenolate mofetil helped reduce steroid use in treating a dog's autoimmune skin disease.

New tests detect finasteride and dutasteride in urine quickly and easily.

New Finasteride conjugate improves prostate treatment and vital signs in rats.

Finasteride safely treats enlarged prostate and male-pattern baldness.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Some herbs show promise as antiandrogenic agents.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

Scutellaria baicalensis extract and baicalin may help prevent hair loss.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Finasteride reduces movement issues in Parkinson's disease rats.

Finasteride helps protect brain in old male rats.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Finasteride helps reduce pain and inflammation in animals.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Topical calcineurin inhibitors, especially 0.1% tacrolimus ointment, are effective and well-tolerated for treating cutaneous lupus erythematosus but require more research for standard treatment guidelines.