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Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Statins may help treat PCOS by lowering androgen levels and improving cholesterol.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Effective PCOS treatments require targeting specific signaling pathways.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.

Ginsenoside Rg3 combined with minoxidil was more effective in treating hair loss in mice.

More research is needed to understand how testosterone is maintained in adult males.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

Androgens reduce BMP2, which weakens the ability of certain cells to help hair stem cells become different types of cells.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

Combining yoga and certain herbs can effectively manage PCOS symptoms and improve quality of life.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.