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Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Melatonin and mitotane treatment led to hair re-growth in 62% of dogs with Alopecia X, but this was not always linked to normal hormone levels.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Propylene glycol and ethanol increase finasteride skin absorption, sodium lauryl sulfate doesn't.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Neutered ferrets often develop hyperadrenocorticism, with symptoms like hair loss and lethargy, and androstenedione is a key indicator for diagnosis.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Brothers of women with PCOS tend to have higher levels of a hormone called DHEAS, indicating a possible genetic link.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

A 3-year-old boy lost all his hair due to a rare reaction to phenobarbital, but it grew back after steroid treatment.

Compound 4 is a promising treatment for hair loss with low toxicity.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

A 20-year-old woman was found to have a rare ovarian tumor causing symptoms like acne and a low-pitched voice, which disappeared after the tumor was removed.

Gut microbes significantly affect brain steroid levels.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Paeonia lactiflora and Poria cocos extracts can potentially increase hair growth and reduce hair loss symptoms by lowering testosterone and inflammation levels.

PSA can help diagnose high androgen levels in women.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Reduced AR gene methylation may cause early pubic hair growth in girls.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Premature balding in some men may be linked to altered hormones, but it's not the male equivalent to polycystic ovary syndrome or metabolic syndrome.

Hair loss in adult females in Makkah is often linked to iron-deficiency anemia and thyroid issues.