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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Finasteride effectively blocks enzyme causing male pattern baldness.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Four-amino acid part makes enzyme sensitive to finasteride.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Intralesional steroid injections are safe and effective for treating severe alopecia areata.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Pulse steroid therapy for alopecia areata shows a 43% complete response rate but has a high relapse rate, especially in children.

Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Hair analysis for stress and reproductive hormones in wildlife needs more research for accuracy across species.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Steroid-binding globulins have important roles beyond just transporting steroids.

Taking finasteride pills and using minoxidil lotion together can help grow hair.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Intralesional steroid therapy is useful for treating various skin conditions.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Most dogs with alopecia had higher than normal levels of certain hormones, but hair loss might not always be linked to these hormone changes.

The steroid solution can regrow hair but often causes skin issues and doesn't work long-term.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Analyzing hair with this method can help understand and monitor scalp conditions and treatment effects.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Dutasteride is more efficient than finasteride, but individual results vary.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.