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Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

The Hairless gene is crucial for healthy skin and hair growth.

Oestrogens are key for bone growth during puberty in both boys and girls.

Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Hormones and signaling pathways control sebaceous gland function and could help treat acne.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Vitamin D is important for bones, hair, blood pressure, and breast development.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Both estrogens and androgens are important for health in both males and females.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.

Certain drugs that block specific enzymes can help treat prostate diseases.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

New treatments for male hypogonadism are effective and should be personalized.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.