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Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Blocking adenosine A2B receptor may prevent or treat hearing loss.

Aryl hydrocarbon receptor overexpression found in miniaturized hair follicles in female hair loss.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

Watercress oil may promote hair growth by activating specific receptors.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Vitamin D3 may protect rat hair follicles from radiation damage.

Different ligands change the shape of the TRPV3 ion channel in unique ways.

Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

The HR protein's role as a repressor is essential for controlling hair growth.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Hormones and genes affect hair growth and male baldness.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Acne in dark skin is influenced by environmental factors and can lead to hyperpigmentation, with various treatment options available.

Some treatments for autoimmune hair loss work, but JAK inhibitors like tofacitinib are promising for regrowth.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Clinicians should use social and prescription data to track trends in performance-enhancing drug use.