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The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Estrogen therapy can reduce skin aging but has cancer risks.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Thiazole, a sulfur and nitrogen chemical, is useful in creating potential drugs for conditions like seizures, cancer, bacterial infections, tuberculosis, inflammation, malaria, viruses, Alzheimer's, diabetes, and A1-receptor issues.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Hsc70 protein may influence hair growth by responding to androgens.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Analog 23 is a promising compound for prostate cancer treatment.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Hair grays due to oxidative stress and fewer functioning melanocytes.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.