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The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Using neurohormones to control keratin can lead to new skin disease treatments.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Mutations in certain receptors can cause diseases and offer new treatment options.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

The vitamin D receptor can work without its usual activating molecule.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

MC4R gene variants not linked to female hair loss.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Prolactin affects when mice shed and grow hair.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.