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This study found that mitotane causes specific changes in cortisol metabolism, including increased excretion of certain metabolites, which may influence cortisol bioavailability without hindering early detection of adrenocortical carcinoma recurrence.

This study describes a new method using high-resolution mass spectrometry for analyzing multiple steroids in human scalp hair, with newborn hair showing the highest steroid concentrations among examined age groups.

This case report described a 9-year-old girl initially suspected to have complete androgen insensitivity syndrome, whose laboratory tests later suggested an alternative diagnosis involving atypical steroid metabolism patterns and hormonal responses.

This review discusses the degenerative effects of anabolic-androgenic steroids on the nervous system and reports no new experimental results, aiming to increase public awareness of their health risks.

This extensive review discusses the clinical manifestations, potential associations, and treatment approaches for lichen planus, but reports no new clinical results, highlighting gaps in evidence for therapeutic strategies.

This review discusses the pathophysiology, diagnosis, and treatment of congenital adrenal hyperplasia, but reports no new research results.

This review discusses the structural and functional advances in understanding sulfotransferases and sulfatases, highlighting new insights into enzyme mechanisms and inactivation by clinically relevant aryl sulfamates, but provides no new experimental results.

This case report describes a patient who developed alopecia after 18 weeks of treatment with dupilumab for atopic dermatitis.

This review discusses the molecular basis and clinical implications of primary generalized glucocorticoid resistance and hypersensitivity, attributing them to mutations in the human glucocorticoid receptor gene, and reports no new clinical findings.

This article reviews the hormonal pathogenesis and treatment strategies for acne vulgaris, particularly in women with severe or treatment-resistant cases, associating it with hormonal imbalances and hyperandrogenism.

This study suggests that 5α-reduced glucocorticoids may have anti-inflammatory potential and could serve as biomarkers for liver inflammation in metabolic disease, with implications for drug development.

In this study, researchers developed a method to measure steroid hormones in hair and found that body hair typically contains higher levels of cortisone and testosterone compared to scalp hair, but hair pigmentation did not affect hormone concentrations significantly.

This review discusses recent advances in understanding the pathogenesis of autoimmune alopecia areata and reports no new clinical results; it highlights potential for developing more effective treatments.

This review discusses the range of cutaneous immune-related adverse events induced by immune checkpoint inhibitors and the proposed mechanisms underlying these skin reactions, but reports no new clinical results.

In this study, researchers found that human ovaries at different life stages biosynthesize both canonical and non-canonical steroid hormones, with fetal ovaries showing higher enzyme activity related to estradiol and testosterone conversion compared to adult tissues.

This review discusses the roles of steroid hormone receptors in lung function related to COVID-19 and outlines ongoing clinical trials of steroid receptor ligands, but reports no new results.

This review emphasizes the potential of repurposing topical L-thyroxine for skin ulcers and telogen effluvium and highlights the need for further exploration of its use in dermatology.

This study found that finasteride-induced androgen deficiency in an animal model resulted in tear deficiency and increased inflammatory cytokine expression in the lacrimal gland, potentially aiding in understanding dry eye pathogenesis.

This review discusses the role of gut steroids in communicating with the gut microbiota and their potential implications in treating gastrointestinal disorders and related brain conditions, suggesting new perspectives on steroid molecules as therapeutic agents.

In this study, researchers identified significant differences in protein expression patterns in scalps affected by central centrifugal cicatricial alopecia, notably upregulation of immune pathways and fibrosis markers and downregulation of metabolic proteins, suggesting unique disease mechanisms and potential therapeutic targets.

This study identified 374 eQTLs in scalp hair follicles associated with genes involved in metabolic, mitotic, immune processes, and responses to steroid hormones, contributing insights into genetic variation and hair traits.

This study found that bulge keratinocytes in mice develop resistance to glucocorticoid treatment more slowly than interfollicular keratinocytes and do not significantly aid in repairing glucocorticoid-induced skin atrophy within five days.

This study found that prolonged use of finasteride in women led to altered levels of sex steroids, DNA damage, and increased menstrual bleeding, suggesting adverse health effects without clear benefits for androgenetic alopecia treatment.

This report on a case of alopecia areata in a mother and daughter with a 16-year gap suggests genetic predisposition and environmental triggers rather than direct transmission.

This source discusses how radiotherapy-induced skin fibrosis, a chronic side effect affecting cancer survivors' quality of life, is driven by ongoing inflammation and fibroblast activity, and emphasizes the need for comprehensive dermatologic management and better diagnostic tools.

This study reports that in human glioblastoma and neuroblastoma cell lines, 24-hydroxycholesterol significantly suppressed the conversion of testosterone to growth-inducing androgens via the 5α-reductase pathway, revealing a new connection between cholesterol homeostasis and androgen metabolism.

In this study, researchers observed that DHEA-induced PCOS rats experienced significant changes in gut microbiota and metabolic profiles, particularly affecting steroid and lipid metabolism, suggesting the gut-ovary axis may play a role in the pathogenesis of PCOS.

This study characterized bioactive compounds in extracts from six Kalimantan herbal plants, confirming traditional medicinal uses with findings such as triterpenoids and several potent compounds with antimicrobial and cardiovascular benefits, laying groundwork for potential therapeutic applications and conservation efforts.

This review supports an autoimmune hypothesis for Satoyoshi syndrome, noting associations with autoantibodies and autoimmune diseases, and reports an observed improvement in most patients with corticosteroid or immunosuppressant treatments.

This study found that steroid hormones influence the quality indicators of fresh and cryopreserved stallion sperm, with testosterone negatively correlated with motility and estradiol positively correlated with survival rate.