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Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Zinc is effective for treating various skin conditions, including warts and acne.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

New treatments for male hypogonadism are effective and should be personalized.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Neurosteroids show promise for treating epilepsy and more research is needed.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.

Testosterone may slow down wound healing and increase inflammation.

DHT, a testosterone byproduct, causes male pattern baldness.