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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

The hair test for vitamin D could be a useful alternative to blood tests, providing a longer-term vitamin D status, but more research is needed.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

BB4CMU rice bran oil may help treat hair loss and gray hair.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Eating a balanced diet with specific nutrients is important for menopausal women to manage hair loss.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Metformin is less effective in men with early-onset hair loss.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Phytotherapeutic compounds and supplements can help manage Polycystic Ovarian Syndrome (PCOS).

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.