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New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Minoxidil can cause deadly skin reaction; monitor patients closely.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.

A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

Men who start losing hair at age 30 may have a lower risk of prostate cancer.

Finasteride doesn't affect ovulation in normal women.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

The new method showed that endometriotic tissue has lower estrogen receptor levels but similar progesterone levels compared to normal endometrium, with both following a similar cycle.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

3α, 17β-androstanediol-glucuronide is not a useful marker for androgen excess but may help monitor certain treatments.

PPAR agonists show promise for skin conditions but need more research before being a main treatment.

Men with hair loss may lack zinc, copper, and vitamin D; supplements could help.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Sulfasalazine can cause severe allergic reactions leading to long-term autoimmune issues like hair loss and skin discoloration.

ADT-G may be a useful indicator of increased androgen levels in women with acne and can be lowered with certain birth control pills.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.