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Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.

The NUDT15 gene variant causes severe side effects from azathioprine in some Indian patients.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Finasteride helps reduce heart enlargement in heart failure patients.

Child with rickets improved with a specific vitamin D therapy, but alopecia did not change.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

New steroids were effective in blocking male hormone receptors in hamster prostates.

Myotonic dystrophy should be considered in patients with hair thinning, and genetic counseling is important.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

AGA treated with finasteride, minoxidil, and hair transplantation.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Hair loss patients may have different polyamine levels in various scalp areas.

The study created a new method to test drugs that affect hormone processing in skin.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.

4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.

Azathioprine may help treat severe alopecia areata, but more research is needed.

Vertex baldness has higher DHT levels than frontal baldness, but testosterone and PSA levels are similar.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.

Testosterone increases sexual behavior in female capuchin monkeys.

A new method found unlisted drugs in two popular hair serums, posing a health risk.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Hormones, especially testosterone and DHT, are key for penis development and function, and testosterone therapy may help with erectile dysfunction in those with low levels.

PCOS is a genetic disorder affecting women's reproductive health, with treatments focused on symptoms like insulin resistance and fertility.

Treatments for hair loss vary, but cell-based options may be the future.

Finasteride improves hair growth in men with androgenetic alopecia.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.