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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Testosterone helps human pancreatic cells increase insulin release.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.

Certain drugs change freshwater snail shells to a "banana" shape.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

DHEA acts like a male hormone on rat skin glands and doesn't turn into female hormones there.

New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.

The herbal hair gel could be a safe hair growth treatment with minimal side effects.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male pattern baldness involves genetics, hormones, and needs better treatments.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.