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Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Mostly postmenopausal Caucasian women get Frontal Fibrosing Alopecia, which often includes eyebrow loss and has limited treatment success.

Current treatments for alopecia show no significant long-term benefits.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Chemotherapy-induced hair loss significantly affects patients' well-being, and nurses are key in helping them cope, but more research is needed to find effective treatments.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

FFA is more common in postmenopausal women, can affect younger women, and may stabilize over time.

Hair loss increases with age; alcohol raises risk, more female partners lowers it.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Minoxidil works better for female hair loss, but cyproterone reduces scalp oiliness and causes menstrual issues.

Finasteride safely lowers DHT levels without affecting testosterone.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Androgenetic alopecia in women needs more research and better management strategies.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

EGFR inhibitors often cause skin problems and other side effects, but these are usually reversible and can be managed to keep patients comfortable.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.