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The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Different ligands change the shape of the TRPV3 ion channel in unique ways.

Compound 4 is a promising treatment for hair loss with low toxicity.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

A natural steroid in the body may protect against eye damage in glaucoma.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

New treatments for male hypogonadism are effective and should be personalized.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Using neurohormones to control keratin can lead to new skin disease treatments.

Mutations in certain receptors can cause diseases and offer new treatment options.

High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.