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A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Vitamin D receptor can control the hairless gene linked to hair loss even without vitamin D.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

New sulfur-containing steroid analogs show promise for more targeted medical treatments.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Gut microbes significantly affect brain steroid levels.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Paeonia lactiflora and Poria cocos extracts can potentially increase hair growth and reduce hair loss symptoms by lowering testosterone and inflammation levels.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

RANK-RANKL signaling is essential for hair growth and skin health.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Skin problems from transplant drugs are common and need careful management in organ transplant patients.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Finasteride causes reduced tear flow and severe eye inflammation.

Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.

New treatments for hair loss are being developed using molecular biology.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Eplerenone, a mineralocorticoid receptor antagonist, was found to promote hair growth in human hair follicles.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Hair growth and health are influenced by stress and hormones.

Testosterone reduces key molecules needed for early pregnancy in rats.

Belimumab reduces disease activity, steroid use, and flares in lupus patients.