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Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Quercetin may help with PCOS symptoms, but more research is needed.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Prolactin may be important for skin growth and immune function.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Finasteride has a higher risk of reproductive side effects than minoxidil.

Androgenic steroids can slow down or stop the growth of certain skin fungi.

A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.

The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Adrenal glands delay the start of winter fur growth in mink.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.