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Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

Ancient hair can preserve hormones, revealing health and fertility insights.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.

The 39th Manfred Donike Workshop discussed methods for detecting misuse of steroids, gene doping, and the complexity of identifying drug residues in urine, highlighting the ongoing efforts to improve global anti-doping work.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

Measuring reproductive hormones in brown bear hair could help identify their sex and reproductive state, but better collection methods or lab techniques are needed.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

A new compound effectively inhibits human 5α-reductase 1.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.

Gingivitis may increase a hormone linked to ovarian function in women with a certain ovary condition, and treating gum disease could help manage it.

Testosterone injections can cause skin darkening and thickening.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

MR antagonists may improve skin health and wound healing, especially in aging.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.