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Tirzepatide might help manage PCOS in obese patients but needs more research to confirm safety and effectiveness.

PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

More research is needed to understand how testosterone is maintained in adult males.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Exemestane may protect bones by stimulating osteoblast growth through androgen-related pathways.

Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.

The document concludes that various skin conditions have specific treatments, ranging from antihistamines for urticaria to surgery and medication for tumors and chronic skin diseases.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

The exact cause of growth hormone-responsive alopecia in dogs is unclear.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

BB4CMU rice bran oil may help treat hair loss and gray hair.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

Different hormones affect hair growth and conditions, with some causing hair loss and others promoting it.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.