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Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.

Prunus mira kernels contain components that can promote hair growth in mice.

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

Stem cell therapies could be a promising alternative for hair loss treatment, but more research is needed to understand their full potential and safety.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

MR antagonists may improve skin health and wound healing, especially in aging.

The document explains how male reproductive hormones work and affect the body.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Gray hair regained color after thyroid hormone treatment.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Spironolactone effectively reduces symptoms of hyperandrogenism but has some side effects.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.