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Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

People with alopecia areata often have lower vitamin D levels and more inflammation, suggesting vitamin D might be involved in the condition.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

The conclusion is that standardizing testosterone measurement methods is essential for better diagnosis accuracy in women.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

A man's health improved after treating his undiagnosed adrenal insufficiency, which caused fatigue and weight loss.

Hair analysis can somewhat track past testosterone levels but is influenced by factors like hair washing, growth rate, sex, and hair color.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.