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17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

The document concludes that the hCG protocol may help in obesity treatment and could be scientifically justified, but more research is needed.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

Dianabol boosts muscle growth but has serious health risks and legal issues.

Stress-related hair loss was reversed with a special medication.

Accurate diagnosis and tailored treatments are crucial for managing hair loss in humans and animals.

Vitamin D is important for bones, hair, blood pressure, and breast development.

μ-Crystallin may help hair growth by affecting thyroid hormone levels in mouse hair follicles.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

Finasteride works better for hair loss in patients 26 or younger.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Researchers found four natural compounds that can change DHT levels in prostate cancer cells.

Segmental hair analysis can track testosterone over time but needs adjustments for sex, hair color, and washing frequency.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.