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An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Pregnancy reduces anxiety in rats, but finasteride reverses this effect.

High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.

Vitamin D3 may protect rat hair follicles from radiation damage.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

A man's health improved after treating his undiagnosed adrenal insufficiency, which caused fatigue and weight loss.

Androstenedione is better than testosterone for diagnosing PCOS in Indian women.

Analyzing bear poop helps measure their stress without harming them.

Gene mutations can cause problems in male genital development.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

New genes and pathways are important for testosterone production and male sexual development.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

People with alopecia areata often have lower levels of vitamin D, zinc, and folate, but more research is needed to understand if supplements can help treat it.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.