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Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Vitamin D is crucial for skin health and managing skin diseases.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Dutasteride makes alcohol less sedating and may lead to less drinking in men.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

New method effectively detects illegal hormones in anti-aging foods.

New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.

PCOS in teens is hard to diagnose, linked to genetics and lifestyle, and managed with weight loss and medication.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

Some hormone treatments might raise breast cancer risk, while others don't seem to.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Too much male hormone in mothers can negatively affect the sexual behavior of both male and female baby mice.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

Endocrine disruptors may cause early hair loss.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

Polycystic ovary syndrome causes high male hormone levels, leading to symptoms like excess hair, acne, and fertility problems.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.

About 19.4% of Iranian women in the study have Polycystic Ovary Syndrome, with the most common type involving irregular periods and high male hormone levels, but their heart and metabolic health is similar to women without the condition.

Sex hormones, especially androgens, play a key role in causing acne.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

A pineal tumor caused a boy's early puberty, which changed from peripheral to central after treatment.

Both estrogens and androgens are important for health in both males and females.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.