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The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Vitamin D3 may protect rat hair follicles from radiation damage.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Finasteride may cause kidney damage.

Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.

MC4R gene variants not linked to female hair loss.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Analyzing bear poop helps measure their stress without harming them.

The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

Treatments for hair loss vary, but cell-based options may be the future.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Vitamin D3 affects cell differentiation in specific skin areas.

Neurosteroids show promise for treating epilepsy and more research is needed.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.