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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

The skin produces and processes hormones, affecting both local and overall body functions.

Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.

Activating c-Myc in skin causes rapid cell growth and changes, but these effects are reversible.

Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

Combining calcipotriol with mometasone is more effective for treating alopecia areata than using mometasone alone.

Mogamulizumab can cause hair loss and skin rashes.

Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

Plant extracts in shampoo improved hair thickness and density in men with hair loss.

Hidradenitis suppurativa is a skin disease caused by the breakdown of the skin's natural immune barriers, especially around hair follicles.

Doxycycline can effectively treat hair loss caused by EGFR inhibitors.

A baby was diagnosed with IFAP syndrome due to a new genetic mutation, showing severe skin and developmental issues.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Treatment with methotrexate and prednisolone led to complete hair regrowth and no relapse for 2 years.

The study found that alopecia areata is strongly linked to autoimmune diseases and may indicate a genetic predisposition to such conditions.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

The study found that certain mutations in the vitamin D receptor can cause rickets and potentially affect hair growth.

VDR regulation varies by tissue and is crucial for its biological functions.

Balanced vitamin D levels are crucial to delay aging and prevent related diseases.

Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.