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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Testosterone is crucial for development, growth, and various body functions in mammals.

Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.

The method accurately measures 19 steroid hormones in human blood and urine using a small sample and is suitable for large-scale monitoring.

Spironolactone effectively reduces symptoms of hyperandrogenism but has some side effects.

Finasteride may cause kidney damage.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

MR antagonists may improve skin health and wound healing, especially in aging.

Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

Vitamin D receptor is crucial for bone health and mineral metabolism.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

A new compound effectively inhibits human 5α-reductase 1.

A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.