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The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

HIV can cause unusual and severe skin problems that are hard to treat.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

People with hair loss have higher risk of high blood sugar and diabetes, and lower levels of a specific hormone.

Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.

Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.

As of 1994, treatments for liver cancer had not significantly improved patient survival.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.