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    Research 121–150 of 1000+

    1. Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride Nature Communications · 2020 · 30 citations
    2. Gas chromatography/mass spectrometry based hair steroid profiling may reveal pathogenesis in hair follicles of the scalp 2011 · 30 citations
    3. Differential expression of steroid 5α-reductase isozymes and association with disease severity and angiogenic genes predict their biological role in prostate cancer Endocrine Related Cancer · 2010 · 30 citations
    4. In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach Journal of Investigative Dermatology Symposium Proceedings · 1999 · 30 citations
    5. Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study BMJ. British medical journal · 2019 · 29 citations
    6. In Vivo Time-Dependent Inhibition of Human Steroid 5a-Reductase by Finasteride Journal of Pharmaceutical Sciences · 1996 · 29 citations
    7. Sexual dimorphism of growth plate prehypertrophic and hypertrophic chondrocytes in response to testosterone requires metabolism to dihydrotestosterone (DHT) by steroid 5‐alpha reductase type 1 Journal of Cellular Biochemistry · 2005 · 27 citations
    8. Effects of mitotane treatment on human steroid metabolism: implications for patient management Endocrine Connections · 2012 · 26 citations
    9. Pharmacogenetic analysis of human steroid 5α reductase type II: comparison of finasteride and dutasteride Journal of Molecular Endocrinology · 2005 · 26 citations
    10. Steroid sulfatase inhibitors Expert Opinion on Therapeutic Patents · 2003 · 25 citations
    11. Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARα and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways Journal of Cellular Biochemistry · 2005 · 24 citations
    12. Effects of sex steroid hormones and their metabolites on neuronal injury caused by oxygen-glucose deprivation/reoxygenation in organotypic hippocampal slice cultures Steroids · 2016 · 24 citations
    13. Roles of steroid sulfatase in brain and other tissues Physiological Research · 2008 · 22 citations
    14. Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-<i>N</i>-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors Journal of Medicinal Chemistry · 2002 · 22 citations
    15. Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone. Biochemical Pharmacology · 2001 · 22 citations
    16. Effect of a novel steroid (PM-9) on the inhibition of 5α-reductase present in Penicillium crustosum broths Steroids · 2003 · 22 citations
    17. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations
    18. High-dose steroid pulse therapy for the treatment of severe alopecia areata. PubMed · 2002 · 21 citations
    19. Inflammation dynamically regulates steroid hormone metabolism and action within macrophages in rheumatoid arthritis Journal of Autoimmunity · 2024 · 20 citations
    20. Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase Tetrahedron Letters · 1995 · 20 citations
    21. Early Intervention with High-Dose Steroid Pulse Therapy Prolongs Disease-Free Interval of Severe Alopecia Areata: A Retrospective Study Annals of Dermatology · 2013 · 19 citations
    22. Consequences of Anabolic-Androgenic Steroid Abuse in Males; Sexual and Reproductive Perspective ˜The œworld journal of men's health · 2021 · 19 citations
    23. Comparative study between fractional carbon dioxide laser vs intralesional steroid injection in treatment of alopecia areata Dermatologic Therapy · 2020 · 18 citations
    24. Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified Experimental Dermatology · 2012 · 18 citations
    25. Steroid Cell Tumor of the Ovary in an Adolescent: A Rare Case Report Case Reports in Medicine · 2013 · 17 citations
    26. Saturable Binding of Finasteride to Steroid 5α-reductase as Determinant of Nonlinear Pharmacokinetics Drug Metabolism and Pharmacokinetics · 2010 · 16 citations
    27. [A case of "syndrome of progressive muscle spasm, alopecia, and diarrhea (Satoyoshi)" treated with steroid pulse therapy]. PubMed · 1992 · 16 citations
    28. Severe steroid-dependent idiopathic angioedema with response to rituximab Annals of Allergy Asthma & Immunology · 2011 · 16 citations
    29. Platelet-Rich Plasma in Alopecia Areata—A Steroid-Free Treatment Modality: A Systematic Review and Meta-Analysis of Randomized Clinical Trials Biomedicines · 2022 · 15 citations
    30. A new label-free screen for steroid 5α-reductase inhibitors using LC-MS Steroids · 2016 · 15 citations