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Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.

Both treatments reduced androgen levels and hair growth in women with hirsutism.

Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.

DHT affects testicular development and regulates spermatogenesis in some fish.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

The study found that certain mutations in the vitamin D receptor can cause rickets and potentially affect hair growth.

Vitamin D helps skin stem cells heal wounds by working with a key skin protein.

Women with excessive hair growth or polycystic ovary disease may more often carry a gene variant for 21 hydroxylase deficiency.

Vitamin D affects Msx1 protein expression and may influence mineralized tissue health.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Baby's toe injury linked to mom's hair loss; check baby's toes and be careful with fruit gel snacks.

Some people have a genetic variation that makes them less effective at breaking down drugs.

Too much androgen can cause hair loss; finasteride may help.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

Finasteride's sexual side effects not caused by androgen deficiency or SRD5A inhibition.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.